Born and raised in Denmark, Anne Sofie Madsen graduated from the Royal Danish Academy of Fine Arts, School of Design. She then trained under John Galliano for Dior in Paris and worked for trend forcasters Peclers, before moving to London to work for Alexander McQueen as a Junior Designer. In 2010 she established her own brand and has had runway shows in Copenhagen, London, New York City, and Saint Petersburg. She also had been asked to showcase her work with Italian Vogue in Milan.
Along with the firm she has been giving lectures, in line with being an external examiner, at the Royal Danish Academy of Fine Arts, School of Design. She has lectured about the design process and the generation of innovation. Along with the development of two annual clothing collections, Anne Sofie Madsen also works as an illustrator, and her work has been published in a range of Danish and international magazines and books.